The fellowship in Pediatric Immunology and Rhematology at Aster CMI, Bangalore offers sub-specialty training to prepare Pediatrics trained physicians for a career in Immunology, Rheumatology and bone marrow transplantation (BMT). This is a 2-year fellowship program designed to train pediatricians to be Pediatric Immunologists and transplant physicians. Led by experienced faculty and supported by an international organization FPID(Foundation for Primary Immunodeficiency Diseases, US), this program offers advanced training in the field of Immunology and BMT.
We have some of the best faculties in the field of Pediatric Immunology and BMT at Aster CMI, Bangalore.
The aim of the program is to provide a structured and formatted advanced training in Pediatric Clinical Immunology encompassing both clinical and laboratory aspects of Immunology. The fellows would get hands on experience in the treatment of these patients including bone marrow transplants. These trained specialists would provide comprehensive specialist care of the highest order and serve as future teachers, trainers and researchers in the field of Pediatric Clinical Immunology. The goal is to train physicians to identify children with immunological diseases (immunodeficiencies, autoimmune and autoinflammatory diseases), perform relevant screening and diagnostic evaluation, use genetic testing rationally and provide genetic counseling. The fellows would be trained in the treatment of such patients including treatment of infections, autoimmunity and the usage of immunoglobulins and biologic medications. The program also intends to train physicians to be competent in the use of hematopoietic cell transplantation and cellular therapy for the treatment of immune deficiencies. We shall train the fellows in indications for transplant; pre-transplant patient evaluation; identification and selection of stem cell sources; use ofdonor registries; methodologies of HLA typing; marrow cryopreservation; management of ABO incompatible cell products; administration of high-dose chemotherapy; management of neutropenic fever; management of bacterial/viral/fungal diseases in immunocompromised patients, diagnosis and management of acute and chronic graft-versus-host disease, late complications of marrow transplantation; as well as training in documentation of all the relevant clinical details. Trainees shall gain experience in bone marrow harvest, stem cell apheresis, stem cell product infusions, and advanced cell processing techniques. Fellows would also complete a research project in Clinical Immunology by the completion of their training program.
Pediatric Immunology and BMT division work in close collaboration with the Department of Pediatrics and Pediatric Intensive Care Unit (PICU) in the hospital. The hospital is equipped with an advanced 12-bed PICU department that has the necessary wherewithal to manage bone marrow and solid organ transplant patients in case of need. The Pediatric Department has a robust teaching program for training pediatric fellows (DNB in Pediatrics, 3-year course), fellowships in Pediatric and Neonatal ICUs. Fellows in the training program would also be actively involved in teaching DNB students.
The Pediatric Immunology and Rheumatology unit was established at Aster CMI Hospital in Feb 2017. The program director Dr. Sagar Bhattad is the first formally trained DM super-specialist in this field in India. He received his training at the prestigious PGIMER institute at Chandigarh, India. The Pediatric Immunology Unit at Aster CMI is the first, and remains till date, the only specialized Pediatric Immunology unit of its kind in the southern state of Karnataka in India. It was established to cater to the needs of children with primary immune deficiency disorders, and children afflicted with various autoimmune and autoinflammatory disorders. Foundation for Primary Immune Deficiency (FPID), an international organization based in the US has recognized the “Pediatric Immunology and Bone marrow transplant” department at Aster CMI as the Centre of Excellence for the diagnosis and management of Primary Immune Deficiencies. This is a unique affiliation conferred to a handful of centers across India. The Pediatric Bone Marrow Transplant Unit at Aster CMI has performed one of the largest numbers of transplants in Immune deficiencies in the country and the team at Aster envisages to build the largest Immunology Centre in South India providing low-cost diagnostic and transplant services to every child with Immune deficiency. Aster CMI Hospital is equipped with state of the art 4-bedded BMT Unit. The unit has all the necessary equipment and infrastructure for performing bone marrow transplants. Dr. Stalin Ramprakash and Dr. Raghuram CP are trained transplant physicians with immense experience in the field.
About the faculty
Dr Sagar Bhattad is the first DM super-specialist in the field of Pediatric Clinical Immunology and Rheumatology in India. He received his training under the mentorship of Prof. Surjit Singh at the prestigious Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh. He has been awarded a Silver medal for MD Pediatrics and Major Gen Amir Chand Gold medal for his research on complement deficiency in Pediatric lupus.
He has a vast experience in the diagnosis and treatment of Primary Immune Deficiency disorders. He is well known amongst medical fraternity for his passion for Immune deficiencies and has delivered numerous lectures and presentations in various forums. Having received extensive training in Clinical and Laboratory Immunology at PGI, Chandigarh, he has been instrumental in setting up the center of excellence in Immunology at Aster CMI hospital.
Dr Sagar Bhattad’s interest in the field of Pediatric Rheumatology led him to Gaslini Institute at Genoa, Italy. This is the largest referral center for Pediatric Rheumatology in Europe. As an observer, he had the opportunity to learn about several novel rheumatologic diseases including the auto-inflammatory diseases. This centre in Italy has the largest collection of auto-inflammatory diseases in the world. He has a special interest in the diagnosis and management of Kawasaki disease and has a large cohort of children with Kawasaki disease under follow-up.
He has written more than twenty-five articles for such peer-reviewed journals like International Journal of Rheumatic Diseases, Journal of Clinical Immunology, Clinical and Experimental Rheumatology, Rheumatology International, Indian Journal of Paediatrics, Indian Paediatrics etc to name a few. He is also a reviewer for the International Journal of Rheumatic diseases and European Journal of Rheumatology. In addition, he has made several presentations at professional conferences and symposia at the national and international levels.
Dr. Stalin Ramprakash is an experienced and dynamic consultant who provides high quality comprehensive care for children with cancer and blood-related problems. He completed his paediatric training in Madras Medical college and pursued further training in the United Kingdom. He completed paediatric training in various London Hospitals and underwent paediatric haematology oncology training in world renowned institutions such as Royal Marsden Hospital, London and Great Ormond Street Hospital, London. He worked as consultant paediatrician with interest in Paediatric Haematology and Oncology for 5 years before returning back to India. His aim is to provide safe, evidence based high quality care at affordable costs in India.
Dr. Ramprakash did his MBBS in 1996 from Madurai Medical college, Madurai, India, MD Paediatrics – 2000 - Institute of Child Health and Hospital for children Madras Medical College, Chennai, India, MRCPCH – 2002, Royal college of Paediatrics and Child Health, UK, CCT (Paediatrics) – 2009 Postgraduate Medical Education and Training Board, UK and FRCPCH - 2011 Royal college of Paediatrics and Child Health, UK.
Dr. C P Raghuram has over 20 years of experience in paediatric oncology, Haematology and BMT and is a consultant Paediatric Haematology, Oncology and BMT at Aster CMI Hospital. He is a Fellow of the Royal College of Physicians (FRCP), Edinburgh, a Member of the Royal College of Paediatrics and Child Health, UK, Indian Academy of Paediatrics and a Member of the National Academy of Medical Sciences, New Delhi.
Dr. Raghuram’s areas of interest include treating children with cancer, children with leukaemia, lymphomas, brain tumours, solid tumours like Wilms tumour, neuroblastomas, bone tumours, soft tissue sarcomas, germ cell tumours, Retinoblastomas including giving high dose treatment and bone marrow transplantation. He treats children with blood disorders like anaemia, low platelet counts and clotting problems. He is involved in bone marrow transplantation for blood and immunological problems.
He obtained Paediatric Higher Specialty Training at the Eastern Deanery Cambridge, UK. He has also undergone Paediatric Oncology training at various tertiary Paediatric Oncology centres in the UK: Christie Hospital-Manchester, Addenbrookes Hospital-Cambridge, Bristol Royal Hospital for Children-Bristol. He was working at the department of Paediatric Oncology at Royal Marsden Hospital, London before moving to India.
Dr. Neha Singh, MD - Dr. Neha is the second fellow in the department of Pediatric Immunology and BMT. She received her MD in Pediatrics from Kasturba Medical College, Mangaluru, and later worked at the prestigious institute of PGIMER, Chandigarh as a Senior Resident. She successfully completed the EULAR / PRES Online Course in Paediatric Rheumatology. Her keen interest in Pediatric Rheumatology and Immunology led her to join the fellowship program at Aster CMI Hospital. She has published many papers and is actively involved in research on Juvenile Idiopathic Arthritis (JIA).
- Singh N, Bhattad S. Autoimmunity and Inborn Errors of Immunity: Two Faces of the Same Coin!. Pediatr Inf Dis. 2022; 4 (4):153-155.
- Jhawar P, Singh N, Bhattad S. Prevention is Better than Cure! Can We prevent Primary Immune Deficiency Diseases?. Pediatr Inf Dis. 2023;5(2):63–64.
- Bhattad S; Mohite R S; Singh N. Growth and Development in Children with Rheumatic Diseases: Maintaining a Balance between Drugs and Disease Activity. Indian Journal of Rheumatology:10.4103/injr.injr_54_22, October 07, 2022. | DOI: 10.4103/injr.injr_54_22
- Bhattad S, Singh N. Inborn errors of Immunity. IAP Case Based reviews in Pediatric Allergy. Jaypee Brothers Medical Publishers (P) Ltd. 2023.p247-256.
- Mortimer PM, Nichols E, Thomas J, Shanbhag R, Singh N, Coomber EL et al. A novel mutation in EROS (CYBC1) causes Chronic Granulomatous Disease. Clin Immunol. 2023 Sep 4:109761.
- Bhattad S, Libre M, Choi JM, Mohite RS, Singh N, Markle JG. Hermansky-Pudlak syndrome with early onset inflammatory bowel disease due to loss of dysbindin expression. Eur J Med Genet. 2023 May 10:104786
- Annual ISKD Conference, Hyderabad, 2022
- Oral presentation : Bilateral Axillary Aneurysms in an infant: Sequelae of Missed Kawasaki Disease
- Infantile versus Non-infantile Kawasaki Disease – A comparative analysis from a tertiary care centre in South India
- Kawasaki disease versus Multi-system Inflammatory Syndrome in Children (MIS-C) – A multicentric comparative analysis from South India
- Acquired phimosis in an infant with IVIG-resistant Kawasaki Disease: A rare occurrence
- Indian Society Of Primary Immune Deficiency(ISPID) IEI Conference, Chandigarh, 2022
- Polyautoimmunity in an Infant with No T-Cells: an Interesting Case of Cd3ε Deficiency and Review Of Literature
- Clinical profile of 14 patients with DOCK8 deficiency: A single-centre experience from Southern India
- Autoimmunity in B Cell Defects - An experience from a tertiary care center in South India
- NCPR, Bangalore, 2022
- Profile of pediatric Systemic Lupus Erythematosus with a special reference to Lupus Nephritis: A five-year single-centre experience from Southern India
- Clinical patterns and causes of uveitis – Experience from a Tertiary Care Centre in Southern India
- Bilateral axillary aneurysms with early thrombotic changes in an infant: The bad sequelae of missed Kawasaki disease!
- Juggling biologics in a child with Tumor Necrosis Factor Receptor Associated Periodic Syndrome – What is the way forward?
- APSID Online Meeting 2022
- Poster titled “Infant presenting with Recurrent Infections and High T cell Counts: An interesting case report of MALT1 deficiency"
- 6th International Conference on Inborn Errors of Immunity, Gurugram, 2023
- Oral presentation titled “A case series of five patients with Activated PI3 Kinase Delta Syndrome: A multicentre center experience"
- Two cases of CBM-opathies—An expanding Spectrum of Inborn Errors of Immunity
- Recurrent pyoderma gangrenosum in three patients with Otulopenia – First of its kind report!
- Profile of 319 Patients With Inborn Errors Of Immunity: A 5-year experience at a tertiary care centre in Southern Indiia
- Profile Of Autoimmunity and Immune Dysregulation in 319 Patients with Inborn Errors Of Immunity At A Tertiary Care Center In South India
- APSID Focussed Webinar on ‘IEI due to GOF or LOF Defects’ 2023
- Oral presentation titled “Immune dysregulation and atypical mycobacteria – The tussle between GOF and LOF!”
- PRES, Netherlands, 2023
- Short communication in Young Investigators Meeting (YIM)
- Profile Of Autoimmunity and Immune Dysregulation in 360 Patients with Inborn Errors Of Immunity At A Tertiary Care Center In South India
Poster presentation in PRESS
- Early onset systemic lupus erythematosus: A case series of four patients with C1Q deficiency
- Spectrum of Systemic Autoinflammatory diseases – Experience from a tertiary care center in South India
- Correlation of disease activity and psychiatric burden of Juvenile Idiopathic Arthritis-Interim analysis of a Prospective Observational Study
- Profile Of Autoimmunity and Immune Dysregulation in 360 Patients with Inborn Errors Of Immunity At A Tertiary Care Center In South India – Selected for the poster tour
- Best poster award won for "Polyautoimmunity in an Infant with No T-Cells: an Interesting Case of Cd3ε Deficiency and Review Of Literature" at IEI 2022, organized by ISPID on November 26-27th, 2022, at PGIMER, Chandigarh.
- Best poster award for the poster titled "Infant presenting with Recurrent Infections and High T cell Counts: An interesting case report of MALT1 deficiency" on 14th December 2022 in APSID online meeting.
Dr. Jyothi Janardhanan, MD - Dr. Jyothi is a young enthusiastic pediatrician interested in the field of Pediatric Immunology and Rheumatology. She completed her MD in Pediatrics from Grant Government Medical College and Sir JJ Group of hospitals, Mumbai, and thereafter completed her senior residency from the same institute. Her profound interest in Pediatric Rheumatology has steered her to join this fellowship at Aster CMI. She is actively involved in research on "Disease activity and outcomes of patients with Inborn Errors of Immunity" at the institution.
Dr. Rachna Shanbhag, MD – Dr. Rachna is the first year fellow, focused in clinical medicine. She received her MD Pediatrics at Smt. Kashibai Navale Medical College, Pune and has been a bright student from her schooling days. Practicing Clinical Immunology has been her dream and she chose Aster for her fellowship for the clinical volume, complexity of cases, the dedicated teaching sessions and the didactic lectures by the faculty in the program.
Achievements of the fellow
- Mohite RS, Kotecha U, Bhattad S. Familial Cold Autoinflammatory Syndrome Type 1. Indian J Pediatr. 2021 Aug;88(8):834.
- Joseph R, Mohite RS, Ginigeri C, Kumar H, Sudheer K, Bhattad S. Hypogammaglobulinemia and periodic fevers–Think of TRNT1 deficiency!. Pediatric Hematology Oncology Journal. 2021 Sep 1;6(3):147-8.
- Mohite RS, Furtado S, Kaur T, Mn V, Bhattad S. Dermatitis herpetiformis in a child with Wiskott-Aldrich syndrome: A rare occurrence. Pediatr Blood Cancer. 2021 Nov 22:e29459.
- Fungal Infections and immune deficiency – Pediatric Infectious disease Journal 2021 Volume 3 Issue 2 (April-June 2021)
- Laboratory clues to primary immunodeficiency diseases - Indian journal of Practical Pediatrics VOLUME 58 JULY 15, 2021
- Is early onset Inflammatory bowel disease a Primary immune deficiency? - Pediatric Infcetious disease Journal 2021, Volume 3:125-127
INDIAN SOCIETY OF PRIMARY IMMUNE DEFICIENCY 2021
- Familial Cold Autoinflammatory Syndrome- First report from the Indian Subcontinent!
- CTLA4-Haplo-insufficiency- A story of 3-generations !
- Hypogammaglobulinemia and periodic fever- Think of TRNT1 deficiency!
- Familial Cold Autoinflammatory syndrome- first report from the Indian subcontinent!
- CTLA4-Haplo-insufficiency- A story of 3-generations !
19th NCPR 2021
- Autoimmunity in a large cohort of Primary Immune Deficiencies – Experience from a tertiary care centre in South India.
- Hypogammaglobulinemia and periodic fever- Think of TRNT1 deficiency!
- Familial Cold Autoinflammatory syndrome- First report from the Indian subcontinent
APSID focused meeting on Phagocytic defects 2021
- Very Early onset IBD in a young boy with oculocutaneous albinism
- Dematiaceous fungal osteomyelitis in an adult with autoimmunity- First report of CGD with EROS mutation from the Indian subcontinent.
- 1st Prize in Oral paper titled ‘Autoimmunity in a large cohort of Primary Immune Deficiencies-Experience from a tertiary care centre in South India’ at the 19th National Conference of Pediatric Rheumatology Society (PRS)
- 1st Prize for oral paper presentation ‘Dematiaceous fungal osteomyelitis in an adult with autoimmunity- First report of CGD with EROS mutation from the Indian subcontinent’ at the APSID focused meeting for Phagocytic defects.
- 2nd Prize for poster presentation ‘Very Early onset IBD in a young boy with oculocutaneous albinism’ at the APSID focused meeting for Phagocytic defects.
Duration of the course
MD (Pediatrics) or DNB (Pediatrics) or an equivalent qualification recognized by the Medical Council of India.
Degree to be awarded
Fellow in Pediatric Clinical Immunology and Bone Marrow Transplant
Number of seats
One candidate would be selected each year. Thus a total of two candidates would registered for the course at any given time.
Applications (online) invited – Month of January, every year
Interview – Month of March, every year
Course begins – 1st April, every year
The fellow shall spend 4 months in the laboratory and get hands on experience in performing immunological tests including flow cytometry. Didactic lectures would be provided by the faculty in the laboratory. The fellow would also be guided to spend at least a week at one of the FPID centers recognized for work in lab immunology, eg: PGIMER, Chandigarh.
Through the guidance of FPID, the fellow will be provided an opportunity to work as an observer for a month in an institute of international repute in Immunology and BMT
Pediatric Immunology and BMT unit at Aster CMI Hospital has been actively involved in clinical research. More than 50 papers have been published by the faculty in several international peer reviewed journals (link). The fellows in the training program will receive the requisite training and guidance in the field of research and shall actively be involved in publishing scientific papers in peer reviewed journals. The fellows shall present papers in national and international congress, providing them the opportunity to interact with leading experts in the field.
Aster CMI Hospital
#43/2, New Airport Road, NH 7, Sahakara
Nagar, Hebbal, Bangalore-560092, India