Dive into the intricate world of Thalassemia as we embark on an insightful journey guided by Dr. Raghuram C P, an esteemed Paediatric Hemato-Oncologist at Aster Group of Hospitals in Bangalore.
Unveiling Thalassemia: Decoding the Genetic Hemoglobin Puzzle:
Within the delicate threads of genetic mutations lies Thalassemia, a hemoglobin disorder skillfully explained by Dr. Raghuram. These mutations give rise to abnormal hemoglobin, triggering a cascade effect on red blood cells and resulting in anemia in affected children.
Symptoms Unveiled: Navigating the Diagnostic Landscape:
Symptoms typically emerge around six months, signaling their presence through fever, cough, and noticeable pallor. Dr. Raghuram emphasizes the pivotal role of early intervention. A blood test, often prompted by observable pallor, unveils severe anemia. Physical examinations may uncover an enlarged liver and spleen, leading to a definitive diagnosis through hemoglobin electrophoresis.
Management through Blood Transfusions and Vigilance Against Infections:
Children grappling with thalassemia major often rely on regular blood transfusions every three to four weeks. Dr. Raghuram underscores the importance of utilizing NAT-tested blood to ward off potential infections. However, repeated transfusions elevate iron levels in critical organs, necessitating medications to regulate these levels. Administering these medications consistently throughout one's life is paramount for effective management.
Challenges and the Path to a Cure:
While ongoing treatments extend a relatively normal life until the age of 30 to 40, complications may surface thereafter. Dr. Raghuram introduces the beacon of hope – a bone marrow transplant. Optimal outcomes are achieved with transplants involving matched siblings. In cases without such matches, alternatives like transplants from unrelated matched donors or half-matched parents, known as haploidentical transplantation, provide avenues for hope.
Leading the Way in Thalassemia Care:
Dr. Raghuram takes pride in showcasing the specialized Bone Marrow Transplant Unit at Aster Group of Hospitals, Bangalore. With a commendable track record of over 250 successful transplants for thalassemia, the Aster Group team stands as a pillar of hope for those seeking curative treatment.
Embark on this enlightening journey with Dr. Raghuram C P, unraveling the complexities of Thalassemia and discovering the transformative potential of bone marrow transplants. Aster Group of Hospitals continues to be a guiding light, ensuring a brighter future for those affected by this condition. Thank you for joining us on this compassionate exploration.