What are the signs & symptoms of Pediatric Craniosynostosis
Following are the common signs and symptoms of pediatric craniosynostosis.
An abnormal feeling or disappearing fontanel (soft spot on the top of the head) Asymmetrical, misshapen skull Development of a raised, hard ridge along with the skull Slow or no growth of the head as the baby grows
These conditions can be corrected with surgery and can restore.
What are the different types of Pediatric Craniosynostosis?
Craniosynostosis can affect babies in two different ways
Isolated craniosynostosis: Isolated craniosynostosis known as non-syndromic craniosynostosis, is the closing of only one suture with no other associated health problems and is the most common kind of craniosynostosis. Syndromic craniosynostosis: Syndromes are when three or more medical problems occur in a recognizable pattern. When craniosynostosis is part of a syndrome, it is known as syndromic craniosynostosis. In these cases, there are usually two or more sutures that closed too early. Patients also have other health conditions as part of the syndrome.
What is Pediatric Craniosynostosis?
The skull is formed by several separate bones. These skull bones are connected by specialized structures called sutures. These sutures look like seams or spaces between the skull bones. The sutures are growth centers for the skull bones. Craniosynostosis is present when one or more of the sutures closes earlier than it should cause the skull to grow into an abnormal shape.
Babies' brains grow very quickly in the first two years of life. As the brain grows it stretches the sutures which signal the sutures to make new bone. The sutures allow the skull to enlarge and create just enough space for the brain. Normally, these sutures remain open until we reach adulthood, long after the brain and skull have stopped growing. Craniosynostosis causes a baby’s skull to misshapen because the brain continues to grow at the same rate even if one or more sutures close too early.
The remaining open sutures have to grow faster to make up for the closed suture. This extra growth causes a change in head shape. In some cases, the remaining open sutures can’t grow fast enough to keep up with the brain’s growth causing abnormally high pressure in the skull, which can have negative effects on brain health. These include learning delays, blindness, and, rarely, death, if untreated.
Do Genetic reasons cause obesity?
Genetic predisposition is one of the reasons for obesity, it is a well-known and currently proven fact. Around 43% of the general population is susceptible to become obese due to genetic factors.
What causes liver cancer?
In some scenarios the cause of liver cancer is identified, for instance chronic hepatitis infection damages the DNA in the liver cells and cause liver cancer. Sometimes liver cancer occurs in patients with no underlying health conditions and it's not clear what causes it.
What is cadaveric transplant?
When the organ for transplantation is obtained from a deceased or brain-dead donor, it is called cadaveric transplant.
What does your liver do?
Produces blood proteins that help your immune system function well, carry oxygen and enable clotting
Stores and releases nutrients to your bloodstream
Produces bile – the enzyme that helps help digest food
Breaks down saturated fat and produces cholesterol out of it
Stores glucose in the form of glycogen
Keeps your body free from toxins.
What are the different types of alcohol-related liver diseases?
The three major liver diseases induced by alcohol are alcoholic fatty liver disease, alcoholic hepatitis and alcoholic cirrhosis.
Alcoholic Fatty Liver
Excess alcohol consumption leads to accumulation of extra fat in your liver.
The first stage of alcohol-related liver disease, this condition usually goes unnoticed as there might be no symptoms at all. However, some patients do present symptoms like unexplained fatigue and weakness. The fat accumulation in the liver will mostly go away by itself if you stop drinking alcohol at this stage. Those who are overweight and have diabetes will need to be extremely careful, for the risk of permanent liver damage is way higher in them.
This is a condition that causes the liver to swell, in turn damaging it. The symptoms of alcoholic hepatitis include loss of appetite, vomiting, abdominal pain, fever and jaundice. It is estimated that one out of every three heavy drinkers develops alcoholic hepatitis.Alcoholic hepatitis can either be mild or severe. Mild liver damage can be reversed; all you need is to quit drinking. However, if one continues to consume alcohol despite having mild alcoholic hepatitis, the liver will slowly start becoming dysfunctional. According to reports, more than 50% of patients with severe alcoholic hepatitis do not survive.
Alcoholic cirrhosis is permanent scarring of liver caused due to excess alcohol consumption. A life-threatening condition and the most serious alcohol-related disease, the liver fails to function normally as healthy liver tissue gets replaced with scar tissue. The damage caused to the liver is usually irreversible.
Though stopping alcohol consumption may help prevent further damage, related complications are not curable.
In addition to the symptoms of alcoholic hepatitis the patient may develop severe bouts of jaundice, vomit blood, suffer from fluid accumulation in the abdomen and feet, get mentally disoriented or worse, slip into coma.
Estimates say that almost 20% of heavy drinkersdevelop liver cirrhosis.
When does one need a liver transplant?
If the liver gets irreparably damaged and cannot be managed medically anymore, your doctor might recommend a liver transplant, depending on your health condition.
What is liver transplant?
Liver transplant, put simply, is the process of replacing the diseased liver with a donated, healthy liver An extremely advanced procedure, it banks heavily on the expertise and experience of the transplant team and of course, high-end medical technology, transplant team and of course, high-end medical technology. There are two types of liver transplant: living donor transplant and cadaveric donor (deceased donor) transplant.
When a healthy person donates part of his or her liver for transplantation, it is called living donor transplant. Living donor liver transplant has its advantages. If someone, preferably a family member is willing to donate part of their liver and the blood type matches, there is no need to wait.
The liver regenerates itself and will grow to its normal size in both the donor and the recipient in 6-8 weeks.
In case there is no live donor available, then one has to wait for cadaveric organ transplant (the liver of a donor who is brain-dead)..In some cases, one donor liver can be transplanted in two people. This is called Split Liver Transplantation.
Worldwide, the success rate of liver transplant- both live and cadaveric - is quite high.
Patients undergoing liver transplantation can expect a success rate of over 90%. We also perform pancreas transplant , which in most cases, is carried out simultaneously with a kidney transplant.